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Botox for Cerebral Palsy

Sep 03rd, 2018 | by NAPA Team


September 03rd, 2018

Alternative Medical Options, Including Botox for Cerebral Palsy

In addition to pediatric physical therapy, there are other medical options for children to help manage cerebral palsy from muscle relaxants to procedures such as Botox. While NAPA physical therapists can help provide some options and talk about those options on a case-by-case basis, this is definitely a topic that your medical doctor is the expert of and we highly recommend talking to them first.

What is Botox and How Can It Help With Cerebral Palsy?

Have you ever heard of botox for cerebral palsy? Botulinum toxin is a drug made from a toxin produced by the bacterium Clostridium botulinum (nlm.nih.gov). As stated by WebMD.com, “when a small amount of Botox is injected into a muscle, it blocks nerve signals that tell your muscles to contract”. It may do wonders in smoothing the wrinkles of adult skin, however, Botox has also been reported to have medical benefits for children with cerebral palsy, especially when paired with occupational and physical therapy.

Botox As a Treatment for Cerebral Palsy: A Look at the Studies

Spasticity, or increased muscle tone, is commonly found in people with CP. For those with spastic (pyramidal) cerebral palsy, muscles are constantly contracting, making limbs stiff, rigid, and resistant to flexing or relaxing. Botox was first reported as a treatment for spasticity in children with CP in 1993 (ncbi.nlm.nih.gov).

  • A review article in Basic Neurosciences, Genetics and Immunology states that there is growing evidence showing the beneficial effects of botulinum toxin type A (BoNT-A) in decreasing muscle tone in children with spasticity associated with CP.
  • In a study from The Journal of Hand Surgery, results show evidence that a statistically higher percentage of children receiving BoNT-A injections show an improvement in the Melbourne Assessment of Unilateral Upper Limb Function compared with those receiving a placebo.
  • The outcome of a study in the Archives of Physical Medicine and Rehabilitation indicates that the combination of BoNT-A and OT results in accelerated attainment of functional goals.
  • Another study from The Journal of International Medical Research concludes that BoNT-A improves muscle tension and motor function, however, rehabilitation following BoNT-A, results in greater improvements to motor function than just BoNT-A alone.
  • The American Academy of Neurology also conducted a study that showed BoNT-A has been established as an effective treatment to reduce spasticity, however, there is conflicting evidence regarding functional improvement.

Find Additional Resources in the NAPA Blog:

For Additional Research:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798879/
  2. http://www.nlm.nih.gov/medlineplus/botox.html
  3. http://www.webmd.com/beauty/botox/botulinum-toxin-botox
  4. http://www.pediatricsdigest.mobi/content/120/1/49.short
  5. http://www.neurology.org/content/74/4/336.full.pdf+html?sid=41e47291-6176-4855-9e61-ed4945e0cfb8
  6. http://www.sciencedirect.com/science/article/pii/S0363502312018084
  7. http://cerebralpalsy.org/about-cerebral-palsy/types/
  8. http://link.springer.com/article/10.1007/s00702-008-0175-8#page-1
  9. http://www.disabilityscoop.com/2010/01/25/botox-cp-2/6744/
  10. http://imr.sagepub.com/content/41/3/636.full


About NAPA Center

At NAPA Center, we take an individualized approach to therapy because we understand that each child is unique with very specific needs. We embrace differences with an understanding that individualized programs work better. For this reason, no two therapeutic programs are alike. If your child needs our services, we will work closely with you to select the best therapies for them, creating a customized program specific to your child’s needs and your family’s goals. Let your child’s journey begin today by contacting us to learn more.

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